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Descriptor English: Bleomycin
Descriptor Spanish: Bleomicina
Descriptor bleomicina
Scope note: Complejo de antibióticos glicopeptídicos relacionados obtenidos de Streptomyces verticillus, constituído por bleomicina A2 y B2. Inhibe el metabolismo del ADN y se utiliza como antineoplásico, especialmente en tumores sólidos.
Descriptor Portuguese: Bleomicina
Descriptor French: Bléomycine
Entry term(s): BLEO cell
BLEO-cell
BLEOcell
Bellon, Bléomycine
Blanoxan
Blenoxane
Bleolem
Bleomicina
Bleomycin A(2)
Bleomycin A2
Bleomycin B(2)
Bleomycin B2
Bleomycin Sulfate
Bleomycins
Bleomycinum Mack
Bléomycine Bellon
Mack, Bleomycinum
Sulfate, Bleomycin
Tree number(s): D09.400.420.110
D12.644.233.110
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001761
Scope note: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
Annotation: a glycopeptide antineoplastic antibiotic
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Registry Number: 11056-06-7
Previous Indexing: Antibiotics, Antineoplastic (1967-1970)
Public MeSH Note: 96; was BLEOMYCINS 1981-95, was BLEOMYCIN 1974-80
History Note: 96; was BLEOMYCINS 1981-95, was BLEOMYCIN 1972-80 (Prov 1972-73)
DeCS ID: 1786
Unique ID: D001761
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Bleomycin - Preferred
Concept UI M0002657
Scope note A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
Preferred term Bleomycin
Entry term(s) Bleomycins
BLEO-cell - Narrower
Concept UI M0460676
Preferred term BLEO-cell
Entry term(s) BLEO cell
BLEOcell
Bleolem - Narrower
Concept UI M0460669
Preferred term Bleolem
Bléomycine Bellon - Narrower
Concept UI M0460677
Preferred term Bléomycine Bellon
Entry term(s) Bellon, Bléomycine
Bleomycin A2 - Narrower
Concept UI M0002654
Preferred term Bleomycin A2
Entry term(s) Bleomycin A(2)
Bleomycin B2 - Narrower
Concept UI M0002655
Preferred term Bleomycin B2
Entry term(s) Bleomycin B(2)
Bleomycin Sulfate - Narrower
Concept UI M0330861
Preferred term Bleomycin Sulfate
Entry term(s) Sulfate, Bleomycin
Bleomycinum Mack - Narrower
Concept UI M0460675
Preferred term Bleomycinum Mack
Entry term(s) Mack, Bleomycinum
Blenoxane - Narrower
Concept UI M0369271
Preferred term Blenoxane
Entry term(s) Blanoxan
Bleomicina - Narrower
Concept UI M0460670
Preferred term Bleomicina



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