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Descriptor English: Ketanserin
Descriptor Spanish: Ketanserina
Descriptor ketanserina
Scope note: Antagonista selectivo de receptores de serotonina que posee propiedades débiles como bloqueante de receptores adrenérgicos. Esta sustancia es efectiva para reducir la presión sanguínea en los casos de hipertensión esencial. Asimismo, es antiagregante plaquetario. Tiene buena tolerancia y es particularmente efectiva en los pacientes de edad.
Descriptor Portuguese: Ketanserina
Descriptor French: Kétansérine
Entry term(s): 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
R 41,468
R 41468
R-41,468
R-41468
R41,468
R41468
Tree number(s): D03.383.621.365
D03.633.100.786.830.333
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007650
Scope note: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Platelet Aggregation Inhibitors
Serotonin Antagonists
Registry Number: 97F9DE4CT4
CAS Type 1 Name: 2,4(1H,3H)-Quinazolinedione, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-
Previous Indexing: Piperidines (1966-1986)
Public MeSH Note: 87
History Note: 87
DeCS ID: 19223
Unique ID: D007650
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/04/09
Revision Date: 2016/05/31
Ketanserin - Preferred
Concept UI M0011983
Scope note A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
Preferred term Ketanserin
Entry term(s) 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
R-41,468 - Narrower
Concept UI M0353421
Preferred term R-41,468
Entry term(s) R 41,468
R 41468
R-41468
R41,468
R41468



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