DeCS

Descriptor English:

Midazolam

Descriptor Spanish:

Midazolam

Spanish from Spain

Descriptor

midazolam

Scope note:

Compuesto hipnótico-sedante de acción rápida, con propiedades ansiolíticas y amnésicas. Se utiliza en odontología, cirugía cardíaca, procedimientos endoscópicos, como medicación preanestésica y como coadyuvante en anestesia local. Debido a su corta duración y estabilidad cardiorrespiratoria, es particularmente útil en pacientes de riesgo, ancianos y cardíacos. Se trata de un compuesto hidrosoluble a pH inferiores a 4, y liposoluble a pH fisiológico.

Descriptor Portuguese:

Midazolam

Descriptor French:

Midazolam

Entry term(s):

Chlorhydrate de midazolam
Maléate de midazolam
Ro 21-3981
Ro213981

Tree number(s):

D03.633.100.079.080.575

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D008874

Scope note:

A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Adjuvants, Anesthesia
Hypnotics and Sedatives
Anti-Anxiety Agents
Anesthetics, Intravenous
GABA Modulators

Registry Number:

R60L0SM5BC

CAS Type 1 Name:

4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-

DeCS ID:

19248

Unique ID:

D008874

NLM Classification:

QV 85