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Descriptor English: Omeprazole
Descriptor Spanish: Omeprazol
Descriptor omeprazol
Scope note: Derivado 4-metoxi, 5-metoxibencimidazol del timoprazol, inhibidor altamente eficaz, de la secreción ácida gástrica, utilizado en el tratamiento de la ÚLCERA GÁSTRICA y en el SÍNDROME DE ZOLLINGER-ELLISON. El fármaco inhibe la H(+)-K(+)-ATPasa de las CÉLULAS PARIETALES GÁSTRICAS.
Descriptor Portuguese: Omeprazol
Descriptor French: Oméprazole
Entry term(s): H 168 68
H 168-68
H 16868
Magnesium, Omeprazole
Omeprazole Magnesium
Omeprazole Sodium
Prilosec
Sodium, Omeprazole
Tree number(s): D02.886.640.074.500
D03.383.725.024.500
D03.633.100.103.034.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009853
Scope note: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Ulcer Agents
Proton Pump Inhibitors
Registry Number: KG60484QX9
CAS Type 1 Name: 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-
Previous Indexing: Benzimidazoles (1966-1986)
Public MeSH Note: 87
History Note: 87
DeCS ID: 19276
Unique ID: D009853
NLM Classification: QV 69
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/06/16
Revision Date: 2016/05/31
Omeprazole - Preferred
Concept UI M0015293
Scope note A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
Preferred term Omeprazole
Prilosec - Narrower
Concept UI M0353567
Preferred term Prilosec
Omeprazole Sodium - Narrower
Concept UI M0583257
Preferred term Omeprazole Sodium
Entry term(s) Sodium, Omeprazole
H 168-68 - Narrower
Concept UI M0353568
Preferred term H 168-68
Entry term(s) H 168 68
H 16868
Omeprazole Magnesium - Narrower
Concept UI M0583258
Preferred term Omeprazole Magnesium
Entry term(s) Magnesium, Omeprazole



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