DeCS

Descriptor English:

Pirenzepine

Descriptor Spanish:

Pirenzepina

Spanish from Spain

Descriptor	pirencepina
Entry term(s)	pirenzepina
Scope note:	Agente antimuscarínico que inhibe la secreción gástrica a dosis más bajas que las requeridas para afectar la motilidad gastrointestinal, la función salivar, el sistema nervioso central, cardiovascular, ocular y urinario. Promueve la cicatrización de la úlcera duodenal y, debido a su acción citoprotectora, es beneficioso en la prevención de la recurrencia de la úlcera duodenal. Potencia también el efecto de otros agentes antiulcerosos tales como CIMETIDINA y RANITIDINA. Suele tener una buena tolerancia.

Descriptor Portuguese:

Pirenzepina

Descriptor French:

Pirenzépine

Entry term(s):

Dichlorhydrate de pirenzépine
LS-519
LS519

Tree number(s):

D03.633.100.079.080.070.750

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D010890

Scope note:

An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anti-Ulcer Agents
Muscarinic Antagonists

Registry Number:

3G0285N20N

CAS Type 1 Name:

6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-

DeCS ID:

19292

Unique ID:

D010890

Documents indexed in the Virtual Health Library (VHL):

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