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Descriptor English: Bromodeoxyuridine
Descriptor Spanish: Bromodesoxiuridina
Descriptor bromodesoxiuridina
Entry term(s) BUdR
BrdU
bromodeoxiuridina
broxuridina
desoxirribósido de bromouracilo
Scope note: Nucleósido que sustituye a la timidina en el ADN, actuando como antimetabolito. Causa roturas en los cromosomas y se ha propuesto como agente antivírico y antineoplásico. Se le ha asignado la consideración de fármaco huérfano para el tratamiento de tumores encefálicos primarios.
Descriptor Portuguese: Bromodesoxiuridina
Descriptor French: Broxuridine
Entry term(s): 5 Bromo 2' deoxyuridine
5 Bromodeoxyuridine
5-Bromo-2'-deoxyuridine
5-Bromodeoxyuridine
BUdR
BrdU
Bromouracil Deoxyriboside
Broxuridine
Deoxyriboside, Bromouracil
NSC-38297
Tree number(s): D03.383.742.680.852.300.150
D13.570.230.430.196
D13.570.685.852.300.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001973
Scope note: A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Antimetabolites, Antineoplastic
Antiviral Agents
Radiation-Sensitizing Agents
Registry Number: G34N38R2N1
CAS Type 1 Name: Uridine, 5-bromo-2'-deoxy-
Public MeSH Note: 66
History Note: 66(65)
DeCS ID: 2002
Unique ID: D001973
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/27
Bromodeoxyuridine - Preferred
Concept UI M0002951
Scope note A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
Preferred term Bromodeoxyuridine
Entry term(s) 5 Bromo 2' deoxyuridine
5 Bromodeoxyuridine
5-Bromo-2'-deoxyuridine
5-Bromodeoxyuridine
BUdR
BrdU
Bromouracil Deoxyriboside
Broxuridine
Deoxyriboside, Bromouracil
NSC-38297 - Narrower
Concept UI M0373518
Preferred term NSC-38297



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