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Descriptor English: Mustard Compounds
Descriptor Spanish: Compuestos de Mostaza
Descriptor compuestos de mostaza
Scope note: Potentes agentes alquilantes e inmunosupresores cuya actividad biológica se basa en la presencia de grupos bis(2-cloretil).. Aunque por lo demás estructuralmente diversos, los compuestos tienen en común la capacidad de contribuir con grupos alquilo al ADN. Son por lo general muy tóxicos pero se incluyen entre ellos muchos agentes antineoplásicos eficaces utilizados ampliamente.
Descriptor Portuguese: Compostos de Mostarda
Descriptor French: Moutardes
Entry term(s): Compounds, Mustard
Tree number(s): D02.455.526.728
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009150
Scope note: Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 68; MUSTARD GAS was heading 1963-67
History Note: 68
Entry Version: MUSTARD CPDS
DeCS ID: 21038
Unique ID: D009150
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 1993/06/03
Mustard Compounds - Preferred
Concept UI M0014270
Scope note Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.
Preferred term Mustard Compounds
Entry term(s) Compounds, Mustard



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