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Descriptor English: RNA Polymerase II
Descriptor Spanish: ARN Polimerasa II
Descriptor ARN polimerasa II
Entry term(s) ARN polimerasa II dependiente de ADN
RNA polimerasa II
RNA polimerasa II DNA-dependiente
RNA polimerasa II dependiente de DNA
Scope note: ARN polimerasa dependiente de ADN, presente en células bacterianas, vegetales y animales. Funciona en la estructura nucleoplasmática y transcribe ADN en ARN. Tiene requerimientos de cationes y sal diferentes de la ARN polimerasa I y resulta fuertemente inhibica por la alfa-amanitina. EC 2.7.7.6.
Descriptor Portuguese: RNA Polimerase II
Descriptor French: RNA polymerase II
Entry term(s): DNA Dependent RNA Polymerase II
DNA-Dependent RNA Polymerase II
RNA Pol II
RNA Polymerase B
Tree number(s): D08.811.913.696.445.735.270.762
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012319
Scope note: A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.7.-
Previous Indexing: RNA Nucleotidyltransferases (1968-1972)
RNA Polymerases (1973-1976)
Public MeSH Note: 84; was see under RNA POLYMERASES 1977-83
History Note: 84(77); was see under RNA POLYMERASES 1977-83
DeCS ID: 21058
Unique ID: D012319
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1976/04/19
Revision Date: 2013/07/08
RNA Polymerase II - Preferred
Concept UI M0019146
Scope note A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
Preferred term RNA Polymerase II
Entry term(s) DNA Dependent RNA Polymerase II
DNA-Dependent RNA Polymerase II
RNA Pol II
RNA Polymerase B



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