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Descriptor English: Factor XII
Descriptor Spanish: Factor XII
Descriptor factor XII
Entry term(s) factor 12
factor XII de la coagulación
factor de Hageman
factor doce
Scope note: Factor estable de la coagulación de la sangre activado por contacto con la superficie subendotelial de un vaso lesionado. Junto con la precalicreína, sirve como factor de contacto que comienza la vía intrínseca de la coagulación de la sangre. La calicreína activa el factor XII a XIIa. La deficiencia del factor XII, también denominada rasgo de Hageman, lleva a una mayor incidencia de enfermedad tromboembólica.
Descriptor Portuguese: Fator XII
Descriptor French: Facteur XII
Entry term(s): Facteur Hageman
Facteur XII de la coagulation
Facteur XII de la coagulation sanguine
Facteur de Hageman
Tree number(s): D08.622.500
D12.776.124.125.450
D12.776.811.243.500
D23.119.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005174
Scope note: Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Entry Combination: deficiency:Factor XII Deficiency
Registry Number: 9001-30-3
CAS Type 1 Name: Blood-coagulation factor XII
Related: Angioedème héréditaire de type III MeSH
Coagulants MeSH
DeCS ID: 22175
Unique ID: D005174
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/02/24
Facteur XII - Preferred
Concept UI M0008158
Preferred term Facteur XII
Entry term(s) Facteur Hageman
Facteur XII de la coagulation
Facteur XII de la coagulation sanguine
Facteur de Hageman



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