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Descriptor English: gamma-Globulins
Descriptor Spanish: gammaglobulinas
Descriptor gamma-globulinas
Entry term(s) gammaglobulina
globulina gamma
globulinas gamma
Scope note: Globulinas séricas que migran a la región gamma (cargadas muy positivamente) en la ELECTROFORESIS. En un momento, las gamma globulinas llegaron a ser utilizadas como sinónimo de inmunoglobulinas ya que la mayoría de las inmunoglobulinas son gamma globulinas y, la inversa, la mayoría de las globulinas gamma son inmunoglobulinas. Pero dado que algunas inmunoglobulinas exhiben una movilidad electroforética alfa o beta, dicho empleo está disminuyendo.
Descriptor Portuguese: gama-Globulinas
Descriptor French: Gammaglobulines
Entry term(s): gamma Globulin
gamma Globulins
gamma-Globulin
Tree number(s): D12.776.124.486.485.397
D12.776.124.790.651.397
D12.776.377.715.548.397
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005719
Scope note: Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
Annotation: /defic = AGAMMAGLOBULINEMIA or DYSGAMMAGLOBULINEMIA; index under IMMUNIZATION, PASSIVE for therapy with gamma-globulins in general or unspecified; anti-gamma globulin antibodies = ANTI-ANTIBODIES (IM) + GAMMA-GLOBULINS (IM); gammopathies: coordinate GAMMA-GLOBULINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA, follow text
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Public MeSH Note: 1996; see GAMMA GLOBULINS 1975-1995, see GAMMA GLOBULIN 1963-1974; /deficiency see GAMMA GLOBULIN DEFICIENCY see AGAMMAGLOBULINEMIA 1963-1967
History Note: 1996 (1963)
DeCS ID: 22183
Unique ID: D005719
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
gamma-Globulins - Preferred
Concept UI M0008973
Scope note Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
Preferred term gamma-Globulins
Entry term(s) gamma Globulin
gamma Globulins
gamma-Globulin



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