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Descriptor English: Prothrombin
Descriptor Spanish: Protrombina
Descriptor protrombina
Entry term(s) factor II
factor II de la coagulación
Scope note: Proteína plasmática que es el precursor inactivo de la trombina. Es convertida en trombina por el complejo de activación de la protrombina, constituido por el factor Xa, el factor V, fosfolípido e iones calcio. La deficiencia de protrombina causa hipoprotrombinemia.
Descriptor Portuguese: Protrombina
Descriptor French: Prothrombine
Entry term(s): Facteur II
Facteur II de la coagulation
Facteur II de la coagulation sanguine
Tree number(s): D08.622.709
D12.776.124.125.800
D12.776.811.243.709
D23.119.945
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011516
Scope note: A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.
Annotation: a blood coag factor; an enzyme precursor
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Entry Combination: deficiency:Hypoprothrombinemias
Registry Number: 9001-26-7
CAS Type 1 Name: Blood-coagulation factor II
Related: Coagulants MeSH
DeCS ID: 22270
Unique ID: D011516
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Prothrombine - Preferred
Concept UI M0017904
Preferred term Prothrombine
Entry term(s) Facteur II
Facteur II de la coagulation
Facteur II de la coagulation sanguine



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