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Descriptor English: Pharmacokinetics
Descriptor Spanish: Farmacocinética
Descriptor farmacocinética
Entry term(s) ADME
ADME-Tox
ADMET
LADMER
absorción, distribución, metabolismo y eliminación
absorción, distribución, metabolismo, eliminación y toxicología
cinética farmacológica
liberación, absorción, distribución, metabolismo, eliminación y respuesta
Scope note: Mecanismos dinámicos y cinéticos de la LIBERACIÓN DE FÁRMACOS, ABSORCIÓN, TRANSPORTE BIOLÓGICO, DISTRIBUCIÓN TISULAR, BIOTRANSFORMACIÓN, eliminación y TOXICIDAD de los productos químicos exógenos y medicamentos en función de la dosis y del METABOLISMO. En este contexto se utilizan los acrónimos LADME (liberación, absorción, distribución, metabolismo y eliminación) y ADME (absorción, distribución, metabolismo y eliminación).
Descriptor Portuguese: Farmacocinética
Descriptor French: Pharmacocinétique
Entry term(s): ADME
ADME-Tox
ADMET
Absorption, Distribution, Metabolism, Elimination, and Toxicology
Absorption, Distribution, Metabolism, and Elimination
Drug Kinetics
Kinetics, Drug
LADMER
Liberation, Absorption, Distribution, Metabolism, Elimination, and Response
Tree number(s): G03.787
G07.690.725
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010599
Scope note: Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.
Annotation: general or unspecified; prefer /pharmacokin with drugs
Allowable Qualifiers: No qualifiers
Previous Indexing: Kinetics (1966-1987)
specific Category D heading/metabolism (1966-1987)
Public MeSH Note: 88
History Note: 88
Entry Version: PHARMACOKIN
DeCS ID: 22960
Unique ID: D010599
NLM Classification: QV 38
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/04/18
Revision Date: 2020/07/22
Pharmacokinetics - Preferred
Concept UI M0016466
Scope note Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.
Preferred term Pharmacokinetics
Entry term(s) Drug Kinetics
Kinetics, Drug
LADMER - Narrower
Concept UI M000676617
Preferred term LADMER
Entry term(s) Liberation, Absorption, Distribution, Metabolism, Elimination, and Response
ADMET - Narrower
Concept UI M000676618
Preferred term ADMET
Entry term(s) ADME-Tox
Absorption, Distribution, Metabolism, Elimination, and Toxicology
ADME - Narrower
Concept UI M000676619
Preferred term ADME
Entry term(s) Absorption, Distribution, Metabolism, and Elimination



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