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Descriptor English: Histones
Descriptor Spanish: Histonas
Descriptor histonas
Scope note: Proteínas cromosómicas pequeñas (aproximadamente 12-20 kD) que poseen una estructura abierta, no plegada y unidas al ADN en los núcleos celulares por enlaces iónicos. La clasificación en diversos tipos (denominadas histona I, histona II, etc) se basa en las cantidades relativas de arginina y de lisina en cada una de ellas.
Descriptor Portuguese: Histonas
Descriptor French: Histone
Entry term(s): Histonine
Tree number(s): D12.776.157.687.485
D12.776.660.720.485
D12.776.664.469
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006657
Scope note: Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
Annotation: H1, H2a, H2b, H3, etc. go here
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
DeCS ID: 23282
Unique ID: D006657
NLM Classification: QU 56
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Histone - Preferred
Concept UI M0010429
Preferred term Histone
Entry term(s) Histonine



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