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Descriptor English: Puromycin
Descriptor Spanish: Puromicina
Descriptor puromicina
Scope note: ADENOSINA cinnamomi que se encuentra en STREPTOMYCES alboniger. Inhibe la sínteis de proteínas al unirse al ARN. Es un agente antineoplásico y antitripanosómico y se utiiliza en investigación como inhibidor de la síntesis proteíca.
Descriptor Portuguese: Puromicina
Descriptor French: Puromycine
Entry term(s): CL-13900
CL13900
Chlorhydrate de puromycine
Dichlorhydrate de puromycine
P-638
P638
Stylomycine
Tree number(s): D02.241.223.200.380
D03.633.100.759.590.138.711
D09.408.051.788
D13.570.583.138.711
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011691
Scope note: A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Protein Synthesis Inhibitors
Trypanocidal Agents
Registry Number: 4A6ZS6Q2CL
CAS Type 1 Name: Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-
DeCS ID: 23434
Unique ID: D011691
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Puromycine - Preferred
Concept UI M0018173
Preferred term Puromycine
P-638 - Narrower
Concept UI M0369376
Preferred term P-638
Entry term(s) P638
Chlorhydrate de puromycine - Narrower
Concept UI M0018174
Preferred term Chlorhydrate de puromycine
Stylomycine - Narrower
Concept UI M0369374
Preferred term Stylomycine
CL-13900 - Narrower
Concept UI M0369375
Preferred term CL-13900
Entry term(s) CL13900
Dichlorhydrate de puromycine - Narrower
Concept UI M0331274
Preferred term Dichlorhydrate de puromycine



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