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Descriptor English: Batroxobin
Descriptor Spanish: Batroxobina
Descriptor batroxobina
Entry term(s) defibrol
hemocoagulasa
Scope note: Enzima proteolítica que se obtiene del veneno de la serpiente terciopelo (Bothrops atrox). Se emplea como agente de coagulación plasmática para el fibrinógeno y para la detección de productos de degradación del fibrinógeno. La presencia de la heparina no interfiere con la prueba de coagulación. La hemocoagulasa es una mezcla que contiene batroxobina y el activador del factor X. EC 3.4.21.-.
Descriptor Portuguese: Batroxobina
Descriptor French: Batroxobine
Entry term(s): Defibrase
Defibrol
Hemocoagulase
Reptilase
Reptilase DEF
Reptilase-DEF
Tree number(s): D08.811.277.656.300.760.955.135
D08.811.277.656.959.350.955.135
D20.888.850.960.200.105
D23.946.833.850.960.200.105
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012103
Scope note: A proteolytic enzyme obtained from the venom of fer-de-lance (Bothrops atrox). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Fibrinolytic Agents
Hemostatics
Registry Number: EC 3.4.21.-
Previous Indexing: Peptide Hydrolases (1969-1974)
Snakes (1969-1974)
Venoms (1969-1974)
Public MeSH Note: 2000; see REPTILASE 1991-1999; see SERINE PROTEINASES 1975-1990; for BATROXOBIN see REPTILASE 1982-199; PLASMOCOAGULASE was indexed under COAGULASE 1979-1999
History Note: 2000(1975); for PLASMOCOAGULASE use BATROXOBIN (NM) 1979-1999
DeCS ID: 23451
Unique ID: D012103
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/07/01
Batroxobin - Preferred
Concept UI M0018820
Scope note A proteolytic enzyme obtained from the venom of fer-de-lance (Bothrops atrox). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-.
Preferred term Batroxobin
Entry term(s) Defibrol
Reptilase-DEF - Narrower
Concept UI M0018821
Preferred term Reptilase-DEF
Entry term(s) Reptilase DEF
Reptilase - Narrower
Concept UI M0333033
Preferred term Reptilase
Defibrase - Narrower
Concept UI M0333034
Preferred term Defibrase
Hemocoagulase - Narrower
Concept UI M0333035
Preferred term Hemocoagulase



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