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Descriptor English: Platelet Activating Factor
Descriptor Spanish: Factor de Activación Plaquetaria
Descriptor factor activador de plaquetas
Entry term(s) AGEPC
PAF aceter
acetil gliceril éter fosforilcolina
factor de activación de plaquetas
factor de activación plaquetaria
fosforilcolina de acetil gliceril éter
éter de acetil glicerol fosforilcolina
Scope note: Derivado fosfolípido formado por PLAQUETAS, BASÓFILOS, NEUTRÓFILOS, MONOCITOS y MACRÓFAGOS. Es un potente agente agregante de las plaquetas e inductor de síntomas anafilácticos sistémicos, incluyendo HIPOTENSIÓN, TROMBOCITOPENIA, NEUTROPENIA y BRONCOCONSTRICCIÓN.
Descriptor Portuguese: Fator de Ativação de Plaquetas
Descriptor French: Facteur d'activation plaquettaire
Entry term(s): 1 Alkyl 2 acetyl sn glycerophosphocholine
1-Alkyl-2-acetyl-sn-glycerophosphocholine
AGEPC
Acetyl Glyceryl Ether Phosphorylcholine
Aggregating Factor, Platelet
Factor, Platelet Activating
PAF Acether
PAF-Acether
Phosphorylcholine, Acetyl Glyceryl Ether
Platelet Activating Substance
Platelet Aggregating Factor
Platelet Aggregation Enhancing Factor
Platelet-Activating Substance
Thrombocyte Aggregating Activity
Tree number(s): D02.033.100.291.211.500
D02.092.063.291.211.500
D02.092.877.883.333.710
D02.675.276.232.710
D10.570.755.375.760.400.985.910
D23.119.865
D23.469.050.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010972
Scope note: A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Lysophosphatidylcholines (1966-1980)
Public MeSH Note: 1983; PLATELET AGGREGATING FACTOR was indexed under PLATLET ACTIVATING FACTOR 2002-2005 & BLOOD COAGULATION FACTORS 1979-2001
History Note: 1983(1979)
DeCS ID: 23518
Unique ID: D010972
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/05/11
Revision Date: 2005/06/30
Platelet Activating Factor - Preferred
Concept UI M0017009
Scope note A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
Preferred term Platelet Activating Factor
Entry term(s) 1 Alkyl 2 acetyl sn glycerophosphocholine
1-Alkyl-2-acetyl-sn-glycerophosphocholine
AGEPC
Acetyl Glyceryl Ether Phosphorylcholine
Aggregating Factor, Platelet
Factor, Platelet Activating
PAF Acether
PAF-Acether
Phosphorylcholine, Acetyl Glyceryl Ether
Platelet Activating Substance
Platelet Aggregating Factor
Platelet Aggregation Enhancing Factor
Platelet-Activating Substance
Thrombocyte Aggregating Activity



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