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| Descriptor English: | Complement Factor B | ||||||
| Descriptor Spanish: |
Factor B del Complemento
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| Descriptor Portuguese: | Fator B do Complemento | ||||||
| Descriptor French: | Facteur B du complément | ||||||
| Entry term(s): |
Bb Fragment of Factor B Bb, Complement Factor C3 Proactivator C3PA Complement 3 Proactivator Complement Factor B Derived Fragment Bb Complement Factor B Fragment, Bb Complement Factor B, Alternative Pathway Complement Factor B-Derived Fragment Bb Complement Factor Ba Complement Factor Bb Complement Protein B Complement Protein Factor B Factor B Factor B, Complement Factor B, Properdin Factor Ba, Complement Factor Ba, Properdin Factor Bb, Complement Factor Bb, Properdin Factor Bf, Properdin Proactivator, C3 Proactivator, Complement 3 Properdin Factor B Properdin Factor Ba Properdin Factor Bb Properdin Factor Bf Properdin Factor Bf F1 Protein B, Complement |
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| Tree number(s): |
D08.622.200 D08.811.277.656.300.760.198 D08.811.277.656.959.350.198 D12.776.124.486.274.900 D12.776.811.243.200 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011415 | ||||||
| Scope note: | A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Immunologic Factors |
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| Registry Number: | EC 3.4.21.47 | ||||||
| Previous Indexing: |
Complement 3 (1975-1977) Enzyme Precursors (1966-1977) Glycoproteins (1966-1977) |
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| Public MeSH Note: | 99; see PROPERDIN FACTOR B 1991-98, see ENZYME PRECURSORS 1978-90; for COMPLEMENT FACTOR B see PROPERDIN FACTOR B 1988-98 |
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| History Note: | 99(78) |
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| DeCS ID: | 23519 | ||||||
| Unique ID: | D011415 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1977/04/15 | ||||||
| Revision Date: | 2009/07/13 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Complement Factor B
- Preferred
Complement Factor Bb
- Narrower
Properdin Factor Bf F1
- Narrower
Properdin Factor Bf
- Narrower
Complement Factor Ba
- Narrower
| Concept UI |
M0017749 |
| Scope note | A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb. |
| Preferred term | Complement Factor B |
| Entry term(s) |
C3 Proactivator C3PA Complement 3 Proactivator Complement Factor B, Alternative Pathway Complement Protein B Complement Protein Factor B Factor B Factor B, Complement Factor B, Properdin Proactivator, C3 Proactivator, Complement 3 Properdin Factor B Protein B, Complement |
| Concept UI |
M0469165 |
| Preferred term | Complement Factor Bb |
| Entry term(s) |
Bb Fragment of Factor B Bb, Complement Factor Complement Factor B Derived Fragment Bb Complement Factor B Fragment, Bb Complement Factor B-Derived Fragment Bb Factor Bb, Complement Factor Bb, Properdin Properdin Factor Bb |
| Concept UI |
M0017752 |
| Preferred term | Properdin Factor Bf F1 |
| Concept UI |
M0017751 |
| Preferred term | Properdin Factor Bf |
| Entry term(s) |
Factor Bf, Properdin |
| Concept UI |
M0017750 |
| Preferred term | Complement Factor Ba |
| Entry term(s) |
Factor Ba, Complement Factor Ba, Properdin Properdin Factor Ba |
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