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Descriptor English: Carmustine
Descriptor Spanish: Carmustina
Descriptor carmustina
Entry term(s) BCNU
Scope note: Agente antineoplásico alquilante inespecífico de la fase del ciclo celular. Se utiliza en el tratamiento de tumores encefálicos y de otras diversas neoplasias malignas. (Martindale, The Extra Pharmacopoeia, 30th ed, p462). Puede anticiparse razonablemente que esta sustancia es carcinógena según el Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Descriptor Portuguese: Carmustina
Descriptor French: Carmustine
Entry term(s): 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
BCNU
BiCNU
FIVB
N,N'-Bis(2-Chloroethyl)-N-Nitrosourea
Nitrumon
Tree number(s): D02.065.950.594.247
D02.654.692.247
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002330
Scope note: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Registry Number: U68WG3173Y
CAS Type 1 Name: Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
Previous Indexing: Alkylating Agents (1966-1971)
Nitroso Compounds (1966-1971)
Urea (1966-1971)
Public MeSH Note: 73
History Note: 73(72)
DeCS ID: 2371
Unique ID: D002330
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Carmustine - Preferred
Concept UI M0003490
Scope note A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
Preferred term Carmustine
Entry term(s) 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
BCNU
FIVB
N,N'-Bis(2-Chloroethyl)-N-Nitrosourea
BiCNU - Narrower
Concept UI M0483979
Preferred term BiCNU
Nitrumon - Narrower
Concept UI M0352089
Preferred term Nitrumon



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