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Descriptor English: | Signal Transduction | ||||||
Descriptor Spanish: |
Transducción de Señal
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Descriptor Portuguese: | Transdução de Sinais | ||||||
Descriptor French: | Transduction du signal | ||||||
Entry term(s): |
Systèmes de transduction du signal Transduction du signal induite par la stimulation des récepteurs Transduction du signal médiée par un récepteur Voies de signalisation cellulaire Voies de transduction des signaux Voies de transduction du signal Voies des signaux de transduction |
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Tree number(s): |
G02.111.820 G04.835 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015398 | ||||||
Scope note: | The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. |
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Allowable Qualifiers: |
DE effets des médicaments et des substances chimiques GE génétique IM immunologie PH physiologie RE effets des radiations |
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Related: |
Canaux ioniques
MeSH | ||||||
DeCS ID: | 23827 | ||||||
Unique ID: | D015398 | ||||||
NLM Classification: | QU 375 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1989/01/01 | ||||||
Date of Entry: | 1988/06/06 | ||||||
Revision Date: | 2019/07/05 |
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PHÉNOMÈNES ET PROCESSUS
Phénomènes chimiques [G02]Phénomènes chimiques -
PHÉNOMÈNES ET PROCESSUS
Phénomènes physiologiques cellulaires [G04]Phénomènes physiologiques cellulaires
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Transduction du signal
- Preferred
Voies de signalisation cellulaire
- Narrower
Voies de transduction du signal
- Narrower
Transduction du signal médiée par un récepteur
- Narrower
Concept UI |
M0023729 |
Preferred term | Transduction du signal |
Entry term(s) |
Systèmes de transduction du signal |
Concept UI |
M0023728 |
Preferred term | Voies de signalisation cellulaire |
Entry term(s) |
Voies des signaux de transduction |
Concept UI |
M0023730 |
Preferred term | Voies de transduction du signal |
Entry term(s) |
Voies de transduction des signaux |
Concept UI |
M0023727 |
Preferred term | Transduction du signal médiée par un récepteur |
Entry term(s) |
Transduction du signal induite par la stimulation des récepteurs |
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