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Descriptor English: Tachykinins
Descriptor Spanish: Taquicininas
Descriptor taquicininas
Scope note: Familia de péptidos biológicamente activos que comparten una secuencia terminal C conservada común, -Fe-X-Gli-Leu-Met-NH2, donde X puede ser o un aminoácido aromático o un aminoácido alifático ramificado. Se han encontrado miembros de esta familia en mamíferos, anfibios y moluscos. Las taquicininas tienen diversas acciones farmacológicas sobre el sistema nervioso central y en los aparatos cardiovascular, génitourinario, respiratorio y digestivo, así como en tejidos glandulares. Esta diversidad de actividad se debe a la existencia de tres o más subtipos de receptores de taquicininas.
Descriptor Portuguese: Taquicininas
Descriptor French: Tachykinines
Entry term(s): Tachykinin
Tree number(s): D12.644.276.812.900
D12.644.400.800
D12.644.456.800
D12.776.467.812.900
D12.776.631.650.800
D23.469.050.375.850
D23.529.812.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015320
Scope note: A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotransmitter Agents
Previous Indexing: Kinins (1966-1988)
Nerve Tissue Proteins (1966-1988)
Neuropeptides (1987-1988)
Oligopeptides (1966-1988)
Peptides (1966-1988)
Public MeSH Note: 89; PHYSALAEMIN was see under KININS 1977-88
History Note: 89; PHYSALAEMIN was see under KININS 1977-88
Related: Receptors, Tachykinin MeSH
DeCS ID: 23846
Unique ID: D015320
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/31
Revision Date: 2015/11/24
Tachykinins - Preferred
Concept UI M0023589
Scope note A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
Preferred term Tachykinins
Entry term(s) Tachykinin



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