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Descriptor English: Sulbactam
Descriptor Spanish: Sulbactam
Descriptor sulbactam
Scope note: Inhibidor de la betalactamasa con muy débil acción antibacteriana. El compuesto previene la destrucción de antibióticos betalactámicos por inhibición de las betalactamasas, ampliando así su espectro de actividad. Combinaciones de sulbactam con antibióticos betalactámicos han sido utilizadas co éxito para el tratamiento de infecciones ocasionadas por organismos resistentes al antibiótico aislado.
Descriptor Portuguese: Sulbactam
Descriptor French: Sulbactam
Entry term(s): CP-45899
CP45899
Sulbactam de sodium
Sulbactam sodique
Tree number(s): D02.065.589.099.750.812
D02.886.108.750.812
D03.633.100.300.750.812
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013407
Scope note: A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Bacterial Agents
beta-Lactamase Inhibitors
Registry Number: S4TF6I2330
CAS Type 1 Name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)-
DeCS ID: 24415
Unique ID: D013407
NLM Classification: QV 354
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/04/09
Revision Date: 2017/05/24
Sulbactam - Preferred
Concept UI M0020733
Preferred term Sulbactam
CP-45899 - Narrower
Concept UI M0351143
Preferred term CP-45899
Entry term(s) CP45899
Sulbactam de sodium - Narrower
Concept UI M0020734
Preferred term Sulbactam de sodium
Entry term(s) Sulbactam sodique



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