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| Descriptor English: | Giant Cells, Langhans | ||||||
| Descriptor Spanish: |
Células Gigantes de Langhans
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| Descriptor Portuguese: | Células Gigantes de Langhans | ||||||
| Descriptor French: | Cellules géantes de Langhans | ||||||
| Entry term(s): |
Cells, Langhans Giant Cells, Langhans-Type Giant Giant Cells, Langhans-Type Langhans Giant Cells Langhans Type Giant Cells Langhans-Type Giant Cells |
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| Tree number(s): |
A11.329.372.380 A11.500.380 A11.627.482.380 A11.733.397.380 A15.382.670.522.380 A15.382.680.397.380 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015744 | ||||||
| Scope note: | Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity. |
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| Annotation: | do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS |
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| Allowable Qualifiers: |
CH chemistry CL classification CY cytology DE drug effects EN enzymology IM immunology ME metabolism MI microbiology PA pathology PH physiology PS parasitology RE radiation effects TR transplantation UL ultrastructure VI virology |
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| Previous Indexing: |
Granuloma, Giant Cell (1977-1989) Macrophages (1966-1989) |
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| Public MeSH Note: | 91; was see under GIANT CELLS 1990 |
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| History Note: | 91(90); was see under GIANT CELLS 1990 |
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| DeCS ID: | 24696 | ||||||
| Unique ID: | D015744 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1989/04/07 | ||||||
| Revision Date: | 2018/06/30 |
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Cells [A11]Cells -
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Cells [A11]Cells -
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Cells [A11]Cells
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Giant Cells, Langhans
- Preferred
| Concept UI |
M0024133 |
| Scope note | Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity. |
| Preferred term | Giant Cells, Langhans |
| Entry term(s) |
Cells, Langhans Giant Cells, Langhans-Type Giant Giant Cells, Langhans-Type Langhans Giant Cells Langhans Type Giant Cells Langhans-Type Giant Cells |
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