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| Descriptor English: | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | ||||||
| Descriptor Spanish: |
1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina
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| Descriptor Portuguese: | 1-Metil-4-Fenil-1,2,3,6-Tetra-Hidropiridina | ||||||
| Descriptor French: | 1-Méthyl-4-phényl-1,2,3,6-tétrahydropyridine | ||||||
| Entry term(s): |
MPTP N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
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| Tree number(s): |
D03.383.725.450 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015632 | ||||||
| Scope note: | A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics RE radiation effects SD supply & distribution ST standards TU therapeutic use UR urine |
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| Entry Combination: |
poisoning:MPTP Poisoning
toxicity:MPTP Poisoning |
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| Pharm Action: |
Neurotoxins Dopamine Agents |
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| Registry Number: | 9P21XSP91P | ||||||
| CAS Type 1 Name: | Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl- | ||||||
| Previous Indexing: |
Pyridines (1966-1989) |
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| Public MeSH Note: | 90 |
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| History Note: | 90 |
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| DeCS ID: | 24779 | ||||||
| Unique ID: | D015632 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1990/01/01 | ||||||
| Date of Entry: | 1989/05/25 | ||||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- Preferred
| Concept UI |
M0023971 |
| Scope note | A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease. |
| Preferred term | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| Entry term(s) |
MPTP N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
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