DeCS

Descriptor English:

Chlorambucil

Descriptor Spanish:

Clorambucilo

Spanish from Spain

Descriptor	clorambucilo
Entry term(s)	clorambucil
Scope note:	Agente alquilante derivado de la mostaza nitrogenada que se utiliza como antineoplásico en la leucemia linfocítica crónica, enfermedad de Hodgkin y otras. Aunque es menos tóxico que la mayoría de las otras mostazas nitrogenadas, ha quedado listado como carcinógeno conocido en el Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

Descriptor Portuguese:

Clorambucila

Descriptor French:

Chlorambucil

Entry term(s):

CB-1348
CB1348
NSC-3088
NSC3088

Tree number(s):

D02.455.526.728.650.156

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D002699

Scope note:

A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antineoplastic Agents, Alkylating

Registry Number:

18D0SL7309

CAS Type 1 Name:

Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-

DeCS ID:

2745

Unique ID:

D002699

Documents indexed in the Virtual Health Library (VHL):

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