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Descriptor English: Chloramphenicol
Descriptor Spanish: Cloranfenicol
Descriptor cloranfenicol
Entry term(s) levomicetina
Scope note: Antibiótico inicialmente aislado de cultivos de Streptomyces venequelae en 1947 que actualmente se produce de forma sintética. Tiene una estructura relativamente simple y fue el primer antibiótico de amplio espectro. Actua por interferencia con la síntesis proteica bacteriana y es principalmente bacteriostático. (Martindale, The Extra Pharmacopoeia, 29th ed, p106).
Descriptor Portuguese: Cloranfenicol
Descriptor French: Chloramphénicol
Tree number(s): D02.033.455.706.300
D02.455.426.559.389.565.175
D02.640.529.175
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002701
Scope note: An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Annotation: an antibiotic
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Bacterial Agents
Protein Synthesis Inhibitors
Registry Number: 66974FR9Q1
CAS Type 1 Name: Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-
DeCS ID: 2747
Unique ID: D002701
NLM Classification: QV 350.5.C5
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/02
Chloramphénicol - Preferred
Concept UI M0004121
Preferred term Chloramphénicol



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