You have selected the view in French
Descriptor English: | Sulindac | ||||
Descriptor Spanish: |
Sulindac
| ||||
Descriptor Portuguese: | Sulindaco | ||||
Descriptor French: | Sulindac | ||||
Entry term(s): |
MK-231 MK231 |
||||
Tree number(s): |
D02.455.426.559.847.486.875 D04.615.486.875 |
||||
RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013467 | ||||
Scope note: | A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. |
||||
Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
||||
Pharm Action: |
Anti-Inflammatory Agents, Non-Steroidal Antineoplastic Agents Cyclooxygenase Inhibitors |
||||
Registry Number: | 184SNS8VUH | ||||
CAS Type 1 Name: | 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)- | ||||
DeCS ID: | 27862 | ||||
Unique ID: | D013467 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1990/01/01 | ||||
Date of Entry: | 1978/02/08 | ||||
Revision Date: | 2016/07/01 |
-
-
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés polycycliques [D04]Composés polycycliques
|
Sulindac
- Preferred
MK-231
- Narrower
Concept UI |
M0020810 |
Preferred term | Sulindac |
Concept UI |
M0350641 |
Preferred term | MK-231 |
Entry term(s) |
MK231 |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey