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Descriptor English: Anti-Inflammatory Agents, Non-Steroidal
Descriptor Spanish: Antiinflamatorios no Esteroideos
Descriptor antiinflamatorios no esteroideos
Entry term(s) AINE
agente antiinflamatorio no esteroideo
agente similar a la aspirina
analgésicos antiinflamatorios
antiinflamatorio no esteroideo
fármacos antiinflamatorios no esteroideos
sustancias similares a la aspirina
Scope note: Fármacos antiinflamatorios no esteroides. Además de tener efectos antiinflamatorios, tienen efectos analgésicos, antipiréticos e inhibidores de las plaquetas. Actúan bloqueando la síntesis de prostaglandinas al inhibir la ciclooxigenasa, que convierte el ácido araquidónico en endoperóxidos cíclicos, precursores de las prostaglandinas. La inhibición de la síntesis de prostaglandinas explica su efecto analgésico, antipirético e inhibidor de las plaquetas; otros mecanismos pueden contribuir a sus efectos antiinflamatorios.
Descriptor Portuguese: Anti-Inflamatórios não Esteroides
Descriptor French: Anti-inflammatoires non stéroïdiens
Entry term(s): AINS
Agents anti-inflammatoires non stéroïdiens
Agents antiinflammmatoires non stéroïdiens
Agents aspirine-like
Analgésiques anti-inflammatoires
Analgésiques antiinflammatoires
Antiinflammatoires non stéroïdiens
Médicaments antiinflammatoires non stéroïdiens
Médicaments aspirine-like
Tree number(s): D27.505.696.663.850.014.040.500
D27.505.954.158.030
D27.505.954.329.030
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000894
Scope note: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
DeCS ID: 27938
Unique ID: D000894
NLM Classification: QV 95
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/06/23
Revision Date: 2020/05/27
Anti-inflammatoires non stéroïdiens - Preferred
Concept UI M0001335
Preferred term Anti-inflammatoires non stéroïdiens
Entry term(s) AINS
Agents anti-inflammatoires non stéroïdiens
Agents antiinflammmatoires non stéroïdiens
Antiinflammatoires non stéroïdiens
Médicaments antiinflammatoires non stéroïdiens
Analgésiques anti-inflammatoires - Narrower
Concept UI M0001334
Preferred term Analgésiques anti-inflammatoires
Entry term(s) Analgésiques antiinflammatoires
Agents aspirine-like - Narrower
Concept UI M0001337
Preferred term Agents aspirine-like
Entry term(s) Médicaments aspirine-like



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