DeCS

Descriptor English:

Erythromycin

Descriptor Spanish:

Eritromicina

Spanish from Spain

Descriptor

eritromicina

Scope note:

Antibiótico macrólido bacteriostático producido por Streptomyces erythreus. Se considera que la eritromicina es su principal componente activo. En los organismos sensibles inhibe la síntesis de proteínas al unirse a las subunidades ribosómicas 50S. Este proceso de unión inhibe la actividad peptidil trransferasa e interfiere en la translocación de los aminoácidos durante la traducción y ensamblaje de las proteínas.

Descriptor Portuguese:

Eritromicina

Descriptor French:

Érythromycine

Entry term(s):

Lactate d'érythromycine
Phosphate d'érythromycine
Érythromycine C

Tree number(s):

D02.540.576.500.992

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D004917

Scope note:

A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anti-Bacterial Agents
Gastrointestinal Agents
Protein Synthesis Inhibitors

Registry Number:

63937KV33D

DeCS ID:

28027

Unique ID:

D004917

NLM Classification:

QV 350.5.E7

Documents indexed in the Virtual Health Library (VHL):

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