DeCS

Descriptor English:

Erythromycin Estolate

Descriptor Spanish:

Estolato de Eritromicina

Spanish from Spain

Descriptor	estolato de eritromicina
Entry term(s)	dodecil sulfato propionato de eritromicina lauril sulfato propionato de eritromicina
Scope note:	Antibiótico macrólido producido por Streptomyces arythreus. Es la sal lauril sulfato del éster propiónico de la eritromicina. Esta sal de eritromicina actúa principalmente como agente bacteriostático. En los organismos sensibles inhibe la síntesis de proteínas al unirse a las subunidades ribosómicas 50S. Este proceso de unión inhibe la actividad peptidil trransferasa e interfiere en la translocación de los aminoácidos durante la traducción y ensamblaje de las proteínas.

Descriptor Portuguese:

Estolato de Eritromicina

Descriptor French:

Érythromycine estolate

Entry term(s):

Estolate d'érythromycine

Tree number(s):

D02.540.576.500.992.250

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D004918

Scope note:

A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anti-Bacterial Agents
Enzyme Inhibitors
Gastrointestinal Agents
Protein Synthesis Inhibitors

Registry Number:

XRJ2P631HP

CAS Type 1 Name:

Erythromycin, 2'-propanoate, dodecyl sulfate (salt)

DeCS ID:

28028

Unique ID:

D004918

Documents indexed in the Virtual Health Library (VHL):

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