| Descriptor English: | Immunotoxins | ||||||
| Descriptor Spanish: |
Inmunotoxinas
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| Descriptor Portuguese: | Imunotoxinas | ||||||
| Descriptor French: | Immunotoxines | ||||||
| Entry term(s): |
Affinotoxin Affinotoxins Antibody Toxin Conjugate Antibody Toxin Conjugates Antibody Toxin Hybrid Antibody Toxin Hybrids Antibody-Toxin Conjugate Antibody-Toxin Conjugate, Monoclonal Antibody-Toxin Conjugates Antibody-Toxin Conjugates, Monoclonal Antibody-Toxin Hybrid Antibody-Toxin Hybrids Carrier, Toxin Carriers, Toxin Chimeric Toxin Chimeric Toxins Conjugate, Antibody-Toxin Conjugate, Cytotoxin-Antibody Conjugate, Monoclonal Antibody-Toxin Conjugate, Toxin Conjugate, Toxin-Antibody Conjugates, Antibody-Toxin Conjugates, Cytotoxin-Antibody Conjugates, Monoclonal Antibody-Toxin Conjugates, Toxin Conjugates, Toxin-Antibody Cytotoxin Antibody Conjugate Cytotoxin Antibody Conjugates Cytotoxin-Antibody Conjugate Cytotoxin-Antibody Conjugates Hybrid, Antibody-Toxin Hybrid, Toxin-Antibody Hybrids, Antibody-Toxin Hybrids, Toxin-Antibody Immunotoxin Monoclonal Antibody Toxin Conjugate Monoclonal Antibody Toxin Conjugates Monoclonal Antibody-Toxin Conjugate Monoclonal Antibody-Toxin Conjugates Targeted Toxin Targeted Toxins Toxin Antibody Conjugate Toxin Antibody Conjugates Toxin Antibody Hybrid Toxin Antibody Hybrids Toxin Carrier Toxin Carriers Toxin Conjugate Toxin Conjugates Toxin, Chimeric Toxin, Targeted Toxin-Antibody Conjugate Toxin-Antibody Conjugates Toxin-Antibody Hybrid Toxin-Antibody Hybrids Toxins, Chimeric Toxins, Targeted |
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| Tree number(s): |
D12.776.124.790.651.114.580.450 D12.776.377.715.548.114.580.450 D27.505.696.477.266.500 D27.888.569.279 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000922 | ||||||
| Scope note: | Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect. |
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| Annotation: | coordinate IM with specific toxin (IM) + specific immune substance (NIM) |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Immunologic Factors |
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| Previous Indexing: |
Antibodies, Monoclonal (1982-1986) Antigens, Surface (1979-1986) Antitoxins (1966-1986) Cytotoxicity, Immunologic (1978-1986) Ricin (1978-1985) |
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| Public MeSH Note: | 90; was ANTIBODY-TOXIN CONJUGATES 1987-89 |
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| Online Note: | use IMMUNOTOXINS to search ANTIBODY-TOXIN CONJUGATES 1987-89 |
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| History Note: | 90; was ANTIBODY-TOXIN CONJUGATES 1987-89 |
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| DeCS ID: | 28229 | ||||||
| Unique ID: | D000922 | ||||||
| NLM Classification: | QW 630.5.I3 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1987/01/01 | ||||||
| Date of Entry: | 1986/03/25 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
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Immunotoxins
- Preferred
Targeted Toxins
- Broader
Toxins, Chimeric
- Broader
| Concept UI |
M0001373 |
| Scope note | Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect. |
| Preferred term | Immunotoxins |
| Entry term(s) |
Affinotoxin Affinotoxins Antibody Toxin Conjugate Antibody Toxin Conjugates Antibody Toxin Hybrid Antibody Toxin Hybrids Antibody-Toxin Conjugate Antibody-Toxin Conjugate, Monoclonal Antibody-Toxin Conjugates Antibody-Toxin Conjugates, Monoclonal Antibody-Toxin Hybrid Antibody-Toxin Hybrids Conjugate, Antibody-Toxin Conjugate, Cytotoxin-Antibody Conjugate, Monoclonal Antibody-Toxin Conjugate, Toxin-Antibody Conjugates, Antibody-Toxin Conjugates, Cytotoxin-Antibody Conjugates, Monoclonal Antibody-Toxin Conjugates, Toxin-Antibody Cytotoxin Antibody Conjugate Cytotoxin Antibody Conjugates Cytotoxin-Antibody Conjugate Cytotoxin-Antibody Conjugates Hybrid, Antibody-Toxin Hybrid, Toxin-Antibody Hybrids, Antibody-Toxin Hybrids, Toxin-Antibody Immunotoxin Monoclonal Antibody Toxin Conjugate Monoclonal Antibody Toxin Conjugates Monoclonal Antibody-Toxin Conjugate Monoclonal Antibody-Toxin Conjugates Toxin Antibody Conjugate Toxin Antibody Conjugates Toxin Antibody Hybrid Toxin Antibody Hybrids Toxin-Antibody Conjugate Toxin-Antibody Conjugates Toxin-Antibody Hybrid Toxin-Antibody Hybrids |
| Concept UI |
M0001375 |
| Preferred term | Targeted Toxins |
| Entry term(s) |
Targeted Toxin Toxin, Targeted Toxins, Targeted |
| Concept UI |
M0001374 |
| Preferred term | Toxins, Chimeric |
| Entry term(s) |
Carrier, Toxin Carriers, Toxin Chimeric Toxin Chimeric Toxins Conjugate, Toxin Conjugates, Toxin Toxin Carrier Toxin Carriers Toxin Conjugate Toxin Conjugates Toxin, Chimeric |
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