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Descriptor English: Cytokines
Descriptor Spanish: Citocinas
Descriptor Portuguese: Citocinas
Descriptor French: Cytokines
Entry term(s): Cytokine
Tree number(s): D12.644.276.374
D12.776.467.374
D23.529.374
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016207
Scope note: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Biological Factors (1989-1990)
Biological Products (1976-1988)
Public MeSH Note: 91
History Note: 91
DeCS ID: 28903
Unique ID: D016207
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/04/24
Revision Date: 2020/01/14
Cytokines - Preferred
Concept UI M0024747
Scope note Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Preferred term Cytokines
Entry term(s) Cytokine



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