DeCS

Descriptor English:

Methacholine Chloride

Descriptor Spanish:

Cloruro de Metacolina

Spanish from Spain

Descriptor	cloruro de metacolina
Entry term(s)	metacolina
Scope note:	Agente de amonio cuaternario, parasimpaticomimético, con las acciones muscarínicas de la ACETILCOLINA. Es hidrolizado por la ACETILCOLINESTERASA a una velocidad considerablemente menor que la ACETILCOLINA y es más resistente a la hidrólisis por COLINESTERASAS no específicas, por lo que sus acciones son más prolongadas. Se utiliza como broncoconstrictor parasimpáticomimético y como auxiliar diagnóstico en el asma bronquial (Martindale, The Extra Pharmacopoeia, 30th ed, p1116).

Descriptor Portuguese:

Cloreto de Metacolina

Descriptor French:

Chlorure de méthacholine

Entry term(s):

Acetyl-beta-methylcholine
Méthacholine

Tree number(s):

D02.092.877.883.555.500
D02.675.276.534.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D016210

Scope note:

A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Miotics
Parasympathomimetics
Bronchoconstrictor Agents
Muscarinic Agonists

Registry Number:

0W5ETF9M2K

CAS Type 1 Name:

1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride

DeCS ID:

29044

Unique ID:

D016210

Documents indexed in the Virtual Health Library (VHL):

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