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Descriptor English: Islets of Langerhans
Descriptor Spanish: Islotes Pancreáticos
Descriptor islotes pancreáticos
Entry term(s) islotes de Langerhans
páncreas endocrino
Scope note: Estructuras microscópicas irregulares constituidas por cordones de células endocrinas distribuidas por todo el PÁNCREAS entre los acinos exocrinos. Cada islote se encuentra rodeado de fibras de tejido conectivo y penetrado de una red de capilares. Existen cuatro principales tipos de células. Las más abundantes son las células beta (50-80 por ciento), secretoras de INSULINA. Las células alfa (5-20 por ciento) segregan GLUCAGÓN. Las células PP (10-35 por ciento) segregan JUGO PANCREÁTICO. Finalmente, las células delta (aproximadamente 5 por ciento) segregan SOMATOSTATINA.
Descriptor Portuguese: Ilhotas Pancreáticas
Descriptor French: Ilots pancréatiques
Entry term(s): Ilots de Langerhans
Pancréas endocrine
Îlots de Langerhans
Îlots pancréatiques
Tree number(s): A03.734.414
A06.300.414
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007515
Scope note: Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Annotation: do not confuse with LANGERHANS CELLS (skin); neoplasms = ADENOMA, ISLET CELL or CARCINOMA, ISLET CELL or their specifics
Allowable Qualifiers: AB malformations
AH anatomie et histologie
BS vascularisation
CH composition chimique
CY cytologie
DE effets des médicaments et des substances chimiques
DG imagerie diagnostique
EM embryologie
EN enzymologie
GD croissance et développement
IM immunologie
IN traumatismes
IR innervation
ME métabolisme
MI microbiologie
PA anatomopathologie
PH physiologie
PP physiopathologie
PS parasitologie
RE effets des radiations
SU chirurgie
UL ultrastructure
VI virologie
Entry Combination: transplantation:Islets of Langerhans Transplantation
DeCS ID: 29211
Unique ID: D007515
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/01
Ilots pancréatiques - Preferred
Concept UI M0011741
Preferred term Ilots pancréatiques
Entry term(s) Ilots de Langerhans
Pancréas endocrine
Îlots de Langerhans
Îlots pancréatiques



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