DeCS

Descriptor English:

Eflornithine

Descriptor Spanish:

Eflornitina

Spanish from Spain

Descriptor	eflornitina
Entry term(s)	alfa-difluorometilornitina difluorometilornitina
Scope note:	Inhibidor de la ORNITINA DESCARBOXILASA, la enzima limitante de la velocidad en la vía biosintética de las poliaminas.

Descriptor Portuguese:

Eflornitina

Descriptor French:

Eflornithine

Entry term(s):

Chlorhydrate d'eflornithine
MDL-71782 A
MDL71782 A
RMI-71782
RMI71782
alpha-Difluorométhylornithine

Tree number(s):

D12.125.068.665.340
D12.125.095.765.340

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000518

Scope note:

An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antineoplastic Agents
Trypanocidal Agents
Ornithine Decarboxylase Inhibitors

Registry Number:

ZQN1G5V6SR

CAS Type 1 Name:

Ornithine, 2-(difluoromethyl)-

DeCS ID:

29232

Unique ID:

D000518

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents