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Descriptor English: Epoprostenol
Descriptor Spanish: Epoprostenol
Descriptor epoprostenol
Entry term(s) Flolan
PGI2
PGX
Veletri
epoprostanol
epoprostenol sódico
prostaciclina
prostaglandina I(2)
prostaglandina I2
Scope note: Prostaglandina que es un potente vasodilatador e inhibe la agregación plaquetaria. Se biosintetiza enzimáticamente a partir de ENDOPERÓXIDOS DE PROSTAGLANDINAS en el tejido vascular humano. La sal sódica se ha utilizado también para tratar la hipertensión pulmonar primaria (HIPERTENSIÓN PULMONAR).
Descriptor Portuguese: Epoprostenol
Descriptor French: Prostacycline
Entry term(s): Epoprosténol
Epoprosténol sodique
PG-I2
PGI-2
PGI2
PGI2 sodique
PGX (Prostaglandine X)
Prostacycline sodique
Prostaglandine I2
Prostaglandine X
Tree number(s): D10.251.355.255.550.550.500
D23.469.050.175.725.550.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011464
Scope note: A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antihypertensive Agents
Platelet Aggregation Inhibitors
Registry Number: DCR9Z582X0
CAS Type 1 Name: Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
DeCS ID: 29280
Unique ID: D011464
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1977/05/23
Revision Date: 2018/03/01
Prostacycline - Preferred
Concept UI M0017816
Preferred term Prostacycline
Entry term(s) Epoprosténol
PG-I2
PGI-2
PGI2
PGX (Prostaglandine X)
Prostaglandine I2
Prostaglandine X
Epoprosténol sodique - Narrower
Concept UI M0017819
Preferred term Epoprosténol sodique
Entry term(s) PGI2 sodique
Prostacycline sodique



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