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Descriptor English: Terfenadine
Descriptor Spanish: Terfenadina
Descriptor terfenadina
Scope note: Antagonisa selectivo de los receptores H1 de histamina desprovisto de actividad depresora sobre el sistema nervioso central. Este fármaco se utilizó para el tratamiento de la ALERGIA pero se retiró por producir el SINDROME DEL QT LARGO.
Descriptor Portuguese: Terfenadina
Descriptor French: Terfénadine
Entry term(s): RMI-9918
RMI9918
Tree number(s): D02.455.426.559.389.115.800
D03.383.621.855
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016593
Scope note: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Histamine H1 Antagonists, Non-Sedating
Registry Number: 7BA5G9Y06Q
CAS Type 1 Name: 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-
DeCS ID: 29787
Unique ID: D016593
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/25
Revision Date: 2017/05/24
Terfénadine - Preferred
Concept UI M0025307
Preferred term Terfénadine
RMI-9918 - Narrower
Concept UI M0351835
Preferred term RMI-9918
Entry term(s) RMI9918



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