| Descriptor English: | Protein Tyrosine Phosphatases | ||||||
| Descriptor Spanish: |
Proteínas Tirosina Fosfatasas
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| Descriptor Portuguese: | Proteínas Tirosina Fosfatases | ||||||
| Descriptor French: | Protein Tyrosine Phosphatases | ||||||
| Entry term(s): |
PTPase Phosphatase, Phosphotyrosine Phosphatase, Phosphotyrosyl Protein Phosphatase, Protein-Tyrosine Phosphatase, Tyrosyl Phosphoprotein Phosphatases, Protein Tyrosine Phosphoprotein Phosphatase, Tyrosyl Phosphotyrosine Phosphatase Phosphotyrosyl Protein Phosphatase Protein Phosphatase, Phosphotyrosyl Protein Tyrosine Phosphatase Protein-Tyrosine Phosphatase Protein-Tyrosine-Phosphatase Tyrosine Phosphatases, Protein Tyrosyl Phosphoprotein Phosphatase |
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| Tree number(s): |
D08.811.277.352.650.775 D12.776.476.564 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017027 | ||||||
| Scope note: | An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. |
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| Annotation: | general; prefer specifics |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.1.3.48 | ||||||
| CAS Type 1 Name: | Protein-tyrosine-phosphate phosphohydrolase | ||||||
| Previous Indexing: |
Phosphoprotein Phosphatases (1985-1991) |
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| Public MeSH Note: | 2008; see PROTEIN-TYROSINE-PHOSPHATASE 1992-2007; PROTEIN-TYROSINE PHOSPHATASE was indexed under PHOSPHOPROTEIN PHOSPHATASES 1985-1991 |
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| History Note: | 2008(1985) |
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| DeCS ID: | 29866 | ||||||
| Unique ID: | D017027 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1992/01/01 | ||||||
| Date of Entry: | 1991/05/30 | ||||||
| Revision Date: | 2007/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Protein Tyrosine Phosphatases
- Preferred
| Concept UI |
M0025868 |
| Scope note | An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. |
| Preferred term | Protein Tyrosine Phosphatases |
| Entry term(s) |
PTPase Phosphatase, Phosphotyrosine Phosphatase, Phosphotyrosyl Protein Phosphatase, Protein-Tyrosine Phosphatase, Tyrosyl Phosphoprotein Phosphatases, Protein Tyrosine Phosphoprotein Phosphatase, Tyrosyl Phosphotyrosine Phosphatase Phosphotyrosyl Protein Phosphatase Protein Phosphatase, Phosphotyrosyl Protein Tyrosine Phosphatase Protein-Tyrosine Phosphatase Protein-Tyrosine-Phosphatase Tyrosine Phosphatases, Protein Tyrosyl Phosphoprotein Phosphatase |
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