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Descriptor English: Pravastatin
Descriptor Spanish: Pravastatina
Descriptor pravastatina
Entry term(s) eptastatina
Scope note: Metabolito fúngico antilipémico aislado de cultivos de Nocardia autotrophica. Actúa como inhibidor competitivo de la HMG Coa reductase (HIDROXIMETILGLUTARIL COA REDUCTASAS).
Descriptor Portuguese: Pravastatina
Descriptor French: Pravastatine
Entry term(s): CS-514
CS514
Eptastatine
Pravastatine de sodium
Pravastatine sodique
RMS-431
RMS431
SQ-31,000
SQ-31000
SQ31,000
SQ31000
Tree number(s): D02.455.426.559.847.638.930
D04.615.638.930
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017035
Scope note: An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number: KXO2KT9N0G
CAS Type 1 Name: 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-
DeCS ID: 29876
Unique ID: D017035
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/07/12
Revision Date: 2016/07/01
Pravastatine - Preferred
Concept UI M0025879
Preferred term Pravastatine
Entry term(s) Eptastatine
CS-514 - Narrower
Concept UI M0350930
Preferred term CS-514
Entry term(s) CS514
Pravastatine de sodium - Narrower
Concept UI M0329324
Preferred term Pravastatine de sodium
Entry term(s) Pravastatine sodique
RMS-431 - Narrower
Concept UI M0350937
Preferred term RMS-431
Entry term(s) RMS431
SQ-31,000 - Narrower
Concept UI M0025880
Preferred term SQ-31,000
Entry term(s) SQ-31000
SQ31,000
SQ31000



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