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Descriptor English: Oxidopamine
Descriptor Spanish: Oxidopamina
Descriptor oxidopamina
Entry term(s) 6-OHDA
6-hidroxidopamin
Scope note: Análogo de neurotransmisor análogo que agota los depósitos noradrenérgicos de las terminaciones nerviosas e induce la reducción de las concentraciones de dopamina en el cerebro. Su mecanismo de acción está relacionado con la producción de radicales libres citolíticos.
Descriptor Portuguese: Oxidopamina
Descriptor French: Oxidopamine
Entry term(s): 6 Hydroxydopamine
6-Hydroxydopamine
6-OHDA
Hydrobromide, Oxidopamine
Hydrochloride, Oxidopamine
Oxidopamine Hydrobromide
Oxidopamine Hydrochloride
Tree number(s): D02.092.311.342.478.650
D02.455.426.559.389.657.166.175.342.478.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016627
Scope note: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Sympatholytics
Adrenergic Agents
Registry Number: 8HW4YBZ748
CAS Type 1 Name: 1,2,4-Benzenetriol, 5-(2-aminoethyl)-
Previous Indexing: Hydroxydopamines (1973-1991)
Public MeSH Note: 92; 6-HYDROXYDOPAMINE was indexed under HYDROXYDOPAMINES 1982-91 & under HYDROXYDOPAMINE 1981
Online Note: use OXIDOPAMINE (NM) to search 6-HYDROXYDOPAMINE (NM) 1980-91
History Note: 92; was 6-HYDROXYDOPAMINE (NM) 1981-91
DeCS ID: 29915
Unique ID: D016627
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/07/12
Revision Date: 2018/07/02
Oxidopamine - Preferred
Concept UI M0025343
Scope note A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
Preferred term Oxidopamine
Entry term(s) 6 Hydroxydopamine
6-Hydroxydopamine
6-OHDA
Oxidopamine Hydrobromide - Narrower
Concept UI M0329482
Preferred term Oxidopamine Hydrobromide
Entry term(s) Hydrobromide, Oxidopamine
Oxidopamine Hydrochloride - Narrower
Concept UI M0329481
Preferred term Oxidopamine Hydrochloride
Entry term(s) Hydrochloride, Oxidopamine



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