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Descriptor English: Clemastine
Descriptor Spanish: Clemastina
Descriptor clemastina
Entry term(s) meclastina
mecloprodin
Scope note: Antagonista de los receptores H1 de histamina utilizado como fumarato hidrogenado en la fiebre del heno, rinitis, dermopatías alérgicas, y prurito. Provoca somnolencia.
Descriptor Portuguese: Clemastina
Descriptor French: Clémastine
Entry term(s): 2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
Clemastine Fumarate
HS 592
HS-592
HS592
Meclastine
Mecloprodin
Tavegyl
Tavist
Tree number(s): D03.383.773.165
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002974
Scope note: A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antipruritics
Histamine H1 Antagonists
Anti-Allergic Agents
Registry Number: 95QN29S1ID
CAS Type 1 Name: Pyrrolidine, 2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methyl-, (R-(R*,R*))-
Previous Indexing: Histamine H1 Receptor Blockaders (1966-1972)
Pyrrolidines (1966-1972)
Public MeSH Note: 91; was see under PYRROLIDINES 1979-90; was MECLASTINE see under PYRROLIDINES 1975-78
Online Note: use CLEMASTINE to search MECLASTINE 1973-78 (as Prov 1973-74)
History Note: 91(79); was see under PYRROLIDINES 1979-90; was MECLASTINE see under PYRROLIDINES 1973-78 (Prov 1973-74)
DeCS ID: 2999
Unique ID: D002974
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Clemastine - Preferred
Concept UI M0004551
Scope note A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Preferred term Clemastine
Entry term(s) 2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
Meclastine
Mecloprodin
Tavist - Narrower
Concept UI M0004552
Preferred term Tavist
Tavegyl - Narrower
Concept UI M0004554
Preferred term Tavegyl
Clemastine Fumarate - Narrower
Concept UI M0004553
Preferred term Clemastine Fumarate
HS-592 - Narrower
Concept UI M0004555
Preferred term HS-592
Entry term(s) HS 592
HS592



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