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Descriptor English: Bone Remodeling
Descriptor Spanish: Remodelación Ósea
Descriptor remodelación ósea
Entry term(s) remodelado óseo
Scope note: Recambio continuo de la MATRIZ ÓSEA y del mineral que contiene, que implica, en primer lugar, un aumento de la RESORCIÓN ÓSEA (actividad osteoclástica) y, posteriormente, una OSTEOGÉNESIS reactiva (actividad osteoblástica). El proceso del remodelado óseo del esqueleto adulto se produce en focos aislados. El proceso asegura la integridad mecánica del esqueleto a lo largo de toda la vida y desempeña un papel importante en la HOMEOSTASIS del calcio. Un desequilibrio en la regulación de los dos acontecimientos opuestos del remodelado óseo, la resorción y la formación óseas, da lugar a muchas de las enfermedades del metabolismo óseo, como la OSTEOPOROSIS.
Descriptor Portuguese: Remodelação Óssea
Descriptor French: Remodelage osseux
Entry term(s): Bone Turnover
Bone Turnovers
Remodeling, Bone
Turnover, Bone
Turnovers, Bone
Tree number(s): G11.427.213
G16.762.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016723
Scope note: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Annotation: note category: an aspect of bone physiol
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Bone Development (1967-1991)
Bone Regeneration (1967-1991)
Bone Resorption (1967-1991)
Public MeSH Note: 92
History Note: 92
DeCS ID: 30227
Unique ID: D016723
NLM Classification: WE 202
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/04/29
Revision Date: 2016/06/02
Bone Remodeling - Preferred
Concept UI M0025466
Scope note The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Preferred term Bone Remodeling
Entry term(s) Bone Turnover
Bone Turnovers
Remodeling, Bone
Turnover, Bone
Turnovers, Bone



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