DeCS

Descriptor English:

Clonazepam

Descriptor Spanish:

Clonazepam

Spanish from Spain

Descriptor	clonazepam
Entry term(s)	5-(2-clorofenil)-1,3-dihidro-7-nitro-2H-1,4-benzodiacepin-2-ona Klonopin
Scope note:	Anticonvulsivante utilizado para diversos tipos de ataques, incluidos los ataques miotónicos o atónicos, epilepsia fotosensible, y crisis de ausencia, aunque puede desarrollar tolerancia. Es poco efectivo en los ataques tónico-clónicos generalizados o parciales. El mecanismo de acción parece ser que está ralacionado con la magnificación de las respuestas de los receptores del ÁCIDO GAMMA-AMINOBUTÍRICO.

Descriptor Portuguese:

Clonazepam

Descriptor French:

Clonazépam

Entry term(s):

Ro 5-4023
Ro54023

Tree number(s):

D03.633.100.079.080.070.150

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D002998

Scope note:

An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anticonvulsants
GABA Modulators

Registry Number:

5PE9FDE8GB

CAS Type 1 Name:

2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-

DeCS ID:

3023

Unique ID:

D002998

Documents indexed in the Virtual Health Library (VHL):

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