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| Descriptor English: | Amyloid beta-Protein Precursor | ||||||
| Descriptor Spanish: |
Precursor de Proteína beta-Amiloide
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| Descriptor Portuguese: | Precursor de Proteína beta-Amiloide | ||||||
| Descriptor French: | Précurseur de la protéine bêta-amyloïde | ||||||
| Entry term(s): |
Amyloid A4 Protein Precursor Amyloid Protein Precursor Amyloid beta Precursor Protein Amyloid beta Protein Precursor Nexin 2, Protease Nexin II, Protease Protease Nexin 2 Protease Nexin II beta Amyloid Protein Precursor beta-Amyloid Protein Precursor beta-Protein Precursor, Amyloid |
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| Tree number(s): |
D12.776.049.407.249 D12.776.543.039 D12.776.811.050 D12.776.815.468.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016564 | ||||||
| Scope note: | A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Amyloid (1988-1991) Protein Precursors (1988-1991) |
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| Public MeSH Note: | 92; AMYLOID BETA-PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN 1990-91 and AMYLOID & PROTEIN PRECURSORS 1988-91; AMYLOID A4 PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN PRECURSOR 1993-94, AMYLOID BETA-PROTEIN 1991-92, PROTEIN PRECURSORS 1987-92, & AMYLOID 1987-90 |
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| Online Note: | use AMYLOID BETA-PROTEIN PRECURSOR (NM) to search AMYLOID BETA-PROTEIN PRECURSOR 1988-91 & AMYLOID A4 PROTEIN PRECURSOR 1987-94 |
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| History Note: | 92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94 |
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| Entry Version: | ABPP |
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| DeCS ID: | 30268 | ||||||
| Unique ID: | D016564 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1992/01/01 | ||||||
| Date of Entry: | 1991/07/12 | ||||||
| Revision Date: | 2013/07/09 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Amyloid beta-Protein Precursor
- Preferred
| Concept UI |
M0025265 |
| Scope note | A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES. |
| Preferred term | Amyloid beta-Protein Precursor |
| Entry term(s) |
Amyloid A4 Protein Precursor Amyloid Protein Precursor Amyloid beta Precursor Protein Amyloid beta Protein Precursor Nexin 2, Protease Nexin II, Protease Protease Nexin 2 Protease Nexin II beta Amyloid Protein Precursor beta-Amyloid Protein Precursor beta-Protein Precursor, Amyloid |
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