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Descriptor English: Lactose Synthase
Descriptor Spanish: Lactosa Sintasa
Descriptor lactosa sintasa
Scope note: Complejo enzimático que cataliza la transferencia de GALACTOSA de la UDP-GALACTOSA a la GLUCOSA, formando LACTOSA. El complejo enzimático consta de una subunidad B, alfa-lactalbúmina, que cambia la especificidad de sustrato de la subunidad A, N-ACETILACTOSAMINA SINTASA, de N-ACETIL-GLUCOSOSAMINA a glucosa, haciendo que la síntesis de lactosa sea la reacción preferente.
Descriptor Portuguese: Lactose Sintase
Descriptor French: Lactose synthase
Entry term(s): Lactose Synthetase
N Acetylgucosamide 1 4 beta Galactosyl Transferase
N-Acetylgucosamide 1-4 beta Galactosyl Transferase
Synthase, Lactose
Synthetase, Lactose
Tree number(s): D05.500.299
D08.811.913.400.450.400.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007788
Scope note: An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.4.1.22
CAS Type 1 Name: UDPgalactose:D-glucose 4-beta-D-galactosyltransferase
Previous Indexing: Glucosyltransferases (1966-1971)
Lactation (1966-1971)
Ligases (1966-1971)
Transferases (1966-1971)
Public MeSH Note: 92; was LACTOSE SYNTHETASE 1974-91
Online Note: use LACTOSE SYNTHASE to search LACTOSE SYNTHETASE 1972-91 (as Prov 1972-73)
History Note: 92: was LACTOSE SYNTHETASE 1972-91 (Prov 1972-73)
DeCS ID: 30378
Unique ID: D007788
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/12
Lactose Synthase - Preferred
Concept UI M0012181
Scope note An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.
Preferred term Lactose Synthase
Entry term(s) Lactose Synthetase
Synthase, Lactose
Synthetase, Lactose
N-Acetylgucosamide 1-4 beta Galactosyl Transferase - Narrower
Concept UI M0012182
Preferred term N-Acetylgucosamide 1-4 beta Galactosyl Transferase
Entry term(s) N Acetylgucosamide 1 4 beta Galactosyl Transferase



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