DeCS

Descriptor English:

Glucuronosyltransferase

Descriptor Spanish:

Glucuronosiltransferasa

Spanish from Spain

Descriptor	glucuronosiltransferasa
Entry term(s)	UDP glucuronosiltransferasa glucuroniltransferasa
Scope note:	Família de enzimas que aceptan una amplia gama de substratos, como fenoles, alcoholes, aminas y ácidos grasos. Funcionan como enzimas metabolizadoras de fármacos, que catalizan la conjugación de ácido UDP-glucurónico a diversos compuestos endógenos y exógenos. EC 2.4.1.17.

Descriptor Portuguese:

Glucuronosiltransferase

Descriptor French:

Glucuronosyltransferase

Tree number(s):

D08.811.913.400.450.480

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D014453

Scope note:

A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.

Annotation:

/defic: consider also CRIGLER-NAJJAR SYNDROME & coord with BILIRUBIN /metab (NIM)

Allowable Qualifiers:

AD administration et posologie
AE effets indésirables
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine

Registry Number:

EC 2.4.1.17

CAS Type 1 Name:

UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)

DeCS ID:

30427

Unique ID:

D014453

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

1977/01/01