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Descriptor English: Protein Prenylation
Descriptor Spanish: Prenilación de Proteína
Descriptor prenilación proteica
Entry term(s) isoprenilación de proteína
isoprenilación de proteínas
isoprenilación postraducción
prenilación de proteína
prenilación de proteínas
Scope note: Modificación post-traduccional de proteínas mediante la unión de un isoprenoide al residuo C-terminal de la cisteína. Los isoprenoides utilizados, el difosfato de farnesilo o el difosfato de geranilgeranilo, derivan del mismo proceso bioquímico que produce el colesterol.
Descriptor Portuguese: Prenilação de Proteína
Descriptor French: Prénylation des protéines
Entry term(s): Farnesylation, Protein
Geranylgeranylation, Protein
Polyisoprenylation, Protein
Post-Translational Isoprenylation
Prenylation, Protein
Protein Farnesylation
Protein Geranylgeranylation
Protein Isoprenylation
Protein Polyisoprenylation
Tree number(s): G02.111.660.871.790.600.400
G02.111.672.500
G02.111.691.600.400
G03.734.871.790.600.400
G03.804.500
G05.308.670.600.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017368
Scope note: A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Protein Processing, Post-Translational (1987-1992)
Public MeSH Note: 2008; see PROTEIN ISOPRENYLATION 1993-2007
History Note: 2008(1993)
DeCS ID: 30594
Unique ID: D017368
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/06/03
Revision Date: 2016/06/23
Protein Prenylation - Preferred
Concept UI M0026380
Scope note A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.
Preferred term Protein Prenylation
Entry term(s) Prenylation, Protein
Protein Polyisoprenylation - Narrower
Concept UI M0026376
Preferred term Protein Polyisoprenylation
Entry term(s) Polyisoprenylation, Protein
Protein Isoprenylation - Narrower
Concept UI M0509377
Preferred term Protein Isoprenylation
Entry term(s) Post-Translational Isoprenylation
Protein Farnesylation - Narrower
Concept UI M0026374
Preferred term Protein Farnesylation
Entry term(s) Farnesylation, Protein
Protein Geranylgeranylation - Narrower
Concept UI M0026375
Preferred term Protein Geranylgeranylation
Entry term(s) Geranylgeranylation, Protein



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