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Descriptor English: Self Tolerance
Descriptor Spanish: Autotolerancia
Descriptor autotolerancia
Entry term(s) auto-tolerancia
Scope note: Ausencia normal de la capacidad para producir una respuesta inmunológica a antígenos autólogos (autoantígenos). Un fallo en la auto-tolerancia lleva a enfermedades autoinmunitarias. La capacidad para reconocer la diferencia entre lo propio y lo que no es propio es la principal función del sistema inmunitario.
Descriptor Portuguese: Tolerância a Antígenos Próprios
Descriptor French: Autotolérance
Entry term(s): Self Tolerances
Tolerance, Self
Tolerances, Self
Tree number(s): G12.535.425.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017634
Scope note: The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.
Annotation: a form of immune tolerance
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Immune Tolerance (1973-1993)
Public MeSH Note: 94
History Note: 94
Related: Autoimmune Diseases MeSH
Clonal Anergy MeSH
Clonal Deletion MeSH
DeCS ID: 31052
Unique ID: D017634
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/02/16
Revision Date: 2016/06/23
Self Tolerance - Preferred
Concept UI M0026701
Scope note The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.
Preferred term Self Tolerance
Entry term(s) Self Tolerances
Tolerance, Self
Tolerances, Self



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