Search
Descriptor English: Itraconazole
Descriptor Spanish: Itraconazol
Descriptor itraconazol
Scope note: Uno de los AGENTES ANTIFÚNGICOS triiazólicos, que inhibe las enzimas dependientes del citocromo P-450, dificultando la síntesis de ERGOSTEROL. Se ha utilizado en el tratamiento de la histoplasmosis, la blastomicosis, la meningitis criptocócica y la aspergilosis.
Descriptor Portuguese: Itraconazol
Descriptor French: Itraconazole
Entry term(s): R-51211
R51211
Tree number(s): D03.383.129.799.550
D03.383.606.530
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017964
Scope note: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antifungal Agents
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: 304NUG5GF4
CAS Type 1 Name: 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-
DeCS ID: 31378
Unique ID: D017964
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/04
Revision Date: 2017/05/24
Itraconazole - Preferred
Concept UI M0027131
Preferred term Itraconazole
R-51211 - Narrower
Concept UI M0353161
Preferred term R-51211
Entry term(s) R51211



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey