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Descriptor English: Connexins
Descriptor Spanish: Conexinas
Descriptor conexinas
Entry term(s) conexina
proteínas gap junction
Scope note: Grupo de proteínas homólogas que forman los canales intermembranas de las UNIONES COMUNICANTES (gap junctions). Las conexinas son productos de una familia de genes identificados que tiene regiones altamente conservadas y altamente divergentes. Esta variedad contribuye al amplio rango de propiedades funcionales de las uniones comunicantes.
Descriptor Portuguese: Conexinas
Descriptor French: Connexines
Entry term(s): Connexin
Gap Junction Channel Proteins
Gap Junction Protein
Gap Junction Proteins
Junction Protein, Gap
Junction Proteins, Gap
Tree number(s): D12.776.543.585.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017630
Scope note: A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Membrane Proteins (1981-1993)
Public MeSH Note: 94; GAP JUNCTION PROTEIN was indexed under MEMBRANE PROTEINS 1982-93
Online Note: use CONNEXINS (NM) to search GAP JUNCTION PROTEIN 1982-93
History Note: 94; GAP JUNCTION PROTEIN was (NM) 1982-93
Related: Erythrokeratodermia Variabilis MeSH
DeCS ID: 31545
Unique ID: D017630
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/08/06
Revision Date: 2020/05/27
Connexins - Preferred
Concept UI M0026696
Scope note A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Preferred term Connexins
Entry term(s) Connexin
Gap Junction Channel Proteins
Gap Junction Protein
Gap Junction Proteins
Junction Protein, Gap
Junction Proteins, Gap



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