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Descriptor English: Telomerase
Descriptor Spanish: Telomerasa
Descriptor telomerasa
Scope note: Ribonucleoproteína trancriptasa reversa esencial, que adiciona ADN telomérico a los extremos de CROMOSOMAS de eucariotas.
Descriptor Portuguese: Telomerase
Descriptor French: Telomerase
Entry term(s): Catalytic Subunit, Telomerase
Reverse Transcriptase, Telomerase
Subunit, Telomerase Catalytic
Telomerase Catalytic Subunit
Telomerase Reverse Transcriptase
Telomerase Reverse Transcriptase Catalytic Subunit
Transcriptase, Telomerase Reverse
Tree number(s): D08.811.913.696.445.308.300.750.750
D12.776.157.687.613
D12.776.157.725.500.921
D12.776.660.720.613
D12.776.664.962.500.921
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019098
Scope note: An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.7.49
Previous Indexing: DNA Nucleotidylexotransferase (1989-1995)
Public MeSH Note: 1996; see DNA NUCLEOTIDYLEXOTRANSFERASE 1989-1995; TELOMERASE REVERSE TRANSCRIPTASE was indexed under DNA-BINDING PROTEINS & TELOMERASE 2000-2006, & under FUNGAL PROTEINS 1997, & under PROTEINS 1997-1999
History Note: 1996(1989); use DNA NUCLEOTIDYLEXOTRANSFERASE 1989-1995
Related: Telomere Homeostasis MeSH
DeCS ID: 32593
Unique ID: D019098
NLM Classification: QU 141
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/06/05
Revision Date: 2017/06/29
Telomerase - Preferred
Concept UI M0028508
Scope note An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
Preferred term Telomerase
Entry term(s) Reverse Transcriptase, Telomerase
Telomerase Reverse Transcriptase
Transcriptase, Telomerase Reverse
Telomerase Catalytic Subunit - Narrower
Concept UI M0496628
Preferred term Telomerase Catalytic Subunit
Entry term(s) Catalytic Subunit, Telomerase
Subunit, Telomerase Catalytic
Telomerase Reverse Transcriptase Catalytic Subunit



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